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Journal of Korean Society Quality Assurance Health Care 1994;1(1): 44.
Published online May 30, 1994.
입원환자에 대한 Ceftazidime의 약물사용 검토
김상현1, 최현숙1, 김향숙1, 신완균1, 손인자1, 조남춘1, 최강원2
1서울대학교병원 약제부
2서울대학교병원 내과
Drug Use Evaluation on Ceftazidime
Sang Hyun Kim1, Hyun Suk Choi1, Hyang Suk Kim1, Wan Gyoon Shin1, In Ja Shon1, Nam Chun Cho1, Kang Won Choi2
1Dept. of Pharmacy
2Dept. of Internal Medicine
Abstract
A drug use evaluation (DUE) program has been defined as an "authorized a quality assurance process designed to ensure that drugs are used appropriately, safely, and effectively". A retrospective DUE study on ceftazidime has been conducted by reviewing patients charts following criteria for drug use evaluation established by Am.S.Hosp.Pharm. Total 60 charts of patient treated with ceftazidime in Seoul National University Hospital from Jan. 1.1993 to July.31.1993 were retrospectively reviewed. As a result, 44 cases(73%) were met with the criteria for the justification of use. In analysing process indicators including culture and sensitivity test, CBC, LFT, history of anaphylaxis monitoring before initial dose, vital sign monitoring were relatively well documented showing the accepted level above 80%, while appropriated dose were infrequently documented with low accepted level. In outcome analysis, blood culture after discontinuing drug were rarely documented, with accepted level of 46%. For using effectively and safely, ceftazidime is recommended to be administrated to optimal indication, and monitored actively for preventing adverse effect.
Key words Ceftazidime;Drug Use Evaluation;Justification of use;Pseudomonas aeruginosa;
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